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Description

(2022) 10:e0270821

Giovanna Varzea Roberti Monteiro de Mattos received the CNPq fellowships (141314/2024-9)

In summary, through pan-cancer analysis using the TIMER database combined with mechanistic integration, this review demonstrates that the activation patterns of the serine synthesis pathway (SSP) in malignant tumors are not randomly distributed, but follow three distinct molecular subtypes: driver mutation-dependent, microenvironmental stress-adaptive, and epigenetic dysregulation subtypes