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Ethics declarations Competing interests The authors declare no conflict of interest

We then assessed the impact of ACOX2 on innate immune cytokine expression

ACS Nano 2 (3), 408418 (2008) S.J

Methylfolate helps power the methylation cycle, which regulates: Homocysteine metabolism Neurotransmitter production (serotonin, dopamine, norepinephrine) Hormone regulation Detoxification and antioxidant production DNA synthesis and repair When the MTHFR gene has a variant (like C677T or A1298C), the enzyme works less efficiently