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It is also vital to the normal function of the nervous and immune system

Importantly, while direct checkpoint blockade aims to reverse T-cell exhaustion, DC-based vaccines address the upstream limitation of insufficient tumor-specific T-cell precursors

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The indication for PPI use was documented in 6,326 encounters (58.2%) with GERD (n=5,127, 47.2%), gastric or duodenal ulcer (n-1,453, 13.4%), and multiple indications (n=1,627, 15.0%) as the most common indications