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Description

via the kynurenine pathway) impairs anti-tumour T cell responses (Wan et al, 2023), although there is limited evidence on whether this increases cancer susceptibility during ageing

The accumulation of senescent cells creates an immunosuppressive environment, promoting viral replication and transmission and thereby accelerating the progression of HIV disease

Amplification of ferroptosis via autophagy and ROS feedback loop There are evidences regarding feedback loop mechanisms in cancer that regulate autophagy and ferroptosis

We acknowledge the financial support in part by DCI Pilot Project, DOD grants (HT9425-24-1-0199, W81XWH-17-1-0143, W81XWH-15-1-0486, W81XWH-19-1-0842, W81XWH-20-1-0907) and NIH grants (R01GM124062, 1R21-AI149205)