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After pre-treatment of iFSP1 (10 M) and/or dicoumarol (20 M), 786-O cells were treated with RSL3 (0.5 M) and indicated concentrations of PK and MK4

Precursors of nicotinamide adenine dinucleotide (NAD + ) in the diet The figure shows the chemical structures of nicotinic acid (pyridine-3-carboxylic acid, which is often referred to as niacin), nicotinamide (pyridine-3-carboxamide, niacinamide), tryptophan, and nicotinamide riboside

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It is superimposed on the fractions of each Niclosamide species (Nic OH and Nic -ve ) (left axis) from the Henderson Hasselbalch analysis (from Figure S3 )