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During the rheumatoid arthritis treatment, the single administration of ascorbic acid, gallic acid or reduced glutathione failed to elicit a continuous antiarthritic effect, finally the symptoms of arthritis would reappear (Supplementary Fig

R., Chaitanya, K

Rengasamy, M

So, after solubilizing glutathione youll want to remeasure the pH of the solution, and add concentrated base to change the pH back to your desired value