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The PI3K/Akt pathway activated by IGF1R is a major anti-apoptotic pathway in neurons, which drives interest in IGF1R agonism as a potential neuroprotective strategy in preclinical research

Synergy of CJC-1295 and Ipamorelin The synergy of combining CJC-1295 with Ipamorelin lies in the two different but complementary mechanisms: CJC-1295 1 gives sustained baseline elevation of GH/IGF-1 (via GHRH receptor stimulation)

(2006) also reported a 50%-200% increase in IGF-1 for about 10 days following a CJC-1295 injection at a dose between 30-250mcg/kg [15] In addition, preclinical experiments involving longer administration periods report that the peptide can have significant benefits for growth and body composition