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When vitamin B12 is bound to transcobalamin I, the plasma turnover shows a half-life of about 9-10 days

Although these results seemed promising, the study had significant limitations in terms of non-randomization, failure to report the severity of ALF, and the unstandardized protocol for the administration of NAC regarding body weight adjustments and administration as a continuous infusion similar to previous studies

However, while adherence rates were high, our review also identified potential usability challenges, particularly in older adults who are unfamiliar with digital technologies