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Peptide therapy is considered to be a very safe form of treatment, with minimal side effects

As senescence plays a role in acute tissue repair, applying senomorphics too early after myocardial infarction may repress wound healing, without permanently addressing persisting cellular senescence as a trigger of chronic maladaptive modelling

Given that FXS is a monogenic cause of ASD, these findings highlight both the challenges of translating GABAergic modulation into broad clinical efficacy and the importance of patient stratification in future trials of targeted therapies for neurodevelopmental disorders (152)