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Peroxisome biogenesis disorders (PBDs) have mainly genetic backgrounds and are caused by incorrect genesis, mainly their assembly, or functional defects of peroxisomes [109]

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2 Moreover, high-intensity exercise may stimulate the immune system leading to an increase in the levels of inflammatory biomarkers including high-sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinases (MMPs) such as MMP2 and MMP9