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Many patients have successfully learnt to self-administer B 12 by intramuscular injection, which reduces both healthcare costs and burden on GP practices, and allows people who are B 12 deficient to optimise their treatment regimen.6566 Case example A man in his 70s presents with a nine month history of difficulty walking and climbing stairs, numbness and pain in his lower limbs, and paraesthesia in his hands

Following ICH, iron accumulation and excessive lipid peroxides trigger ferroptosis