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Early mucosal changes, such as adenomatous polyps, do not consistently show low B12 levels, suggesting the deficiency may develop later, as the disease progresses

In this type of anemia, people lack intrinsic factor in the stomach which is necessary for the absorption of the vitamin

The National Institute of Health (NIH) added: "Even at large doses, vitamin B12 is generally considered to be safe because the body does not store excess amounts." Vitamin B12 supplementation does, however, have a greater risk of interacting with other medications than leading to toxicity side effects