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Furthermore, scientific outcome assessments should not only incorporate a range of scales, but also consider objective indicators such as autonomic nervous system (ANS) activity and neurotransmitter levels, as these may elucidate underlying mechanisms of acupuncture in gastrointestinal dysmotility

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These hypotheses have sprung from its perceived potential to stimulate the production of collagen, elastin, and glycosaminoglycans, crucial intercellular matrix components

In addition, the bioavailability of HMs may be improved by the use of chelating compounds and microorganisms, which, in turn, facilitates their accumulation in plants (Olaniran et al., 2013)