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Common signs and symptoms of perimenopause Here is a list of notable symptoms associated with perimenopause to look out for as youre assessing your own experience with this transition: Body odor changes Brain fog Breast soreness Cycle changes Fatigue Frequent urination Hair loss Heart palpitations Insomnia/trouble sleeping Joint pain Low libido Mood changes Night sweats/hot flashes Period changes Spotting Weight gain Vaginal dryness and painful sex [2, 8] Remember that although these are common, your body is unique and you may not experience some (or any) of these symptoms

[DOI] [PubMed] [Google Scholar] 142.Kelley RK, Cheng A-L, Braiteh FS, Park J-W, Benzaghou F, Milwee S, Borgman A, El-Khoueiry AB, Kayali ZK, Zhu AX, Rimassa L

A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation

doi: 10.1186/s12883-019-1500-6, 45