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In p38-deficient mice, inflammasome hyperactivity resulted in pulmonary inflammation and heightened susceptibility to septic shock

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Coffee leaf tea extracts elevate multiple SCFAs including acetate, propionate, butyrate, and valerate, and this increase in SCFAs is associated with reduced XOD activity (Zhou et al., 2023)

For instance, infliximab and adalimumab is recommended by the clinical community, which are based on anti-inflammatory small-molecule medicines, have limited therapeutic efficacy, and cause serious complications [99]