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The development of cystic acne is largely influenced by genetics, but various external factors can also contribute to its onset

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This engineering was necessary to reduce the proliferative effect of native FGF19 on hepatocytes, mediated via signaling through FGFR4the only FGF receptor at which FGF19 and FGF21 differ in agonist activity (305)

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Concomitantly, metabolomic analysis showed significant differences between aged WT and Mda5 -/- HSCs

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