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doi:10.1016/1046-5928(92)90001-D Pan F, Qiu YL (2006) Chin J Pharm 37(4):237239 Acknowledgments The authors express their appreciation to the financial support obtained from the National Science Foundation of China (20636010, 20406002 and 50373003), National High-tech Project 863 (2006AA02Z245), and Chinese National 973 Project (2007CB714304)

Other diseases involving TDP-43 pathological developments are primary lateral sclerosis and progressive muscular atrophy, and together these four diseases are known as TDP-proteinopathies (Figure 1) (Dugger and Dickson, 2017)