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10698962 52WheelerMD.ThurmanRG

Parallel evolution of senescence in annual fishes in response to extrinsic mortality

Activation of PKA also increases NOX activity and colocalization of NOX and G6PD

The prolonged opening of this pore affects the redox state of the mitochondria, impairs oxidative phosphorylation, and activates apoptosis, ultimately leading to cell death