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Description

On examination, there are central dendritic corneal erosions that stain poorly with fluorescein

Without sufficient blood supply, tissue repair stalls and skin quality deteriorates

These mutations in the GyrA and ParC subunits are situated within the quinolone resistance-determining region (QRDR), specifically close to the active site tyrosines (Tyr122 for GyrA and Tyr120 for ParC) of these enzymes (Ostrer et al., 2019)