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High-fat diets cause dysfunctional gut microbiota, decreases the abundance of gut microbiota and decreases the ratio of beneficial to harmful intestinal bacteria (94)

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On the other hand, a more recent study using the complemented donor acceptor bioluminescence resonance energy transfer (CODA-RET) technique demonstrated a D 4.7 R heteromerization-dependent gain of function of the D 2 R ( CODA-RET is a BRET assay that allows the measurement of ligand-induced changes in the interaction between G protein-coupled receptors (GPCRs) forming specific homomers or heteromers with transducer proteins, including G proteins ( Renilla Luciferase are separately fused to two different receptor molecules putatively able to oligomerize and a fluorescent chromophore (such as yellow fluorescent protein) can be fused to a G protein subunit

10.1111/acel.12939 67 XingH