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it is required for over 300 reactions that take place in the body, playing a crucial role in mental health, energy production, sleep, blood sugar regulation, cognitive function, and many other aspects of wellness

Ann Clin Transl Neurol 5:10891103

Tran, C.D

Subsequently, Nuclear Factor Erythroid 2-related Factor 2 (NRF2) was identified as a transcription factor involved in regulating gene expression at these ARE sequences (Itoh et al., 1997