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S., Morris E

Alternatively, the second composition may include a first amount of a second exogenous mRNA that is different from the first exogenous mRNA

In practice, stacking multiplies uncertainty: more compounds more chances of impurity/contamination more pathways affected more interaction risk more variables harder to know what helped (or harmed) If you take only one clinical principle from this article: the more experimental the stack, the more conservative your risk posture should be