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Furthermore, miR-200a-3p enriched EVs derived from healthy astrocytes decline the expression of mitogen-activated protein kinase 4 (MKK4), a crucial kinase in the c-Jun N-terminal kinase apoptotic pathway (146)

High extra-cellular K levels activate the K channels in osteoblasts and osteoclasts, specifically the inwardly rectifying K and voltage-gated K channels