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10.1021/jf201053s J Agric Food Chem

Prediction of EF-hand calcium-binding proteins and analysis of bacterial EF-hand proteins

By reinforcing this barrier, it prevents the translocation of luminal antigens and endotoxins into the bloodstream, a key pathological driver in many chronic inflammatory and autoimmune conditions

This was supported by Bester et al., who demonstrated that IL-1, IL-6, and IL-8 (proinflammatory cytokines) promote whole-blood hypercoagulability and alter erythrocyte membrane structure