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An in vitro study of human bronchial epithelial cells from patients with COPD or asthma showed that increased oxidant burden may lead to reduced corticosteroid responsiveness in airway epithelium, with important consequences for the integrity of the epithelial barrier and associated production of pro-inflammatory cytokines [43]

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In view of a considerable variety of enzymes involved in the metabolism of GSH, their changing activities in redox reaction and their potential roles in the prediction and therapeutic significance in preeclampsia can be of an intriguing discipline to pursue