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mentioned that oxidized mtDNA would be cleaved into segments and subsequently transported to the cytoplasm in two steps

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Human mitochondrial chaperone (mtHSP70) and cysteine desulfurase (NFS1) bind preferentially to the disordered conformation, whereas co-chaperone (HSC20) binds to the structured conformation of the ironsulfur cluster scaffold protein (ISCU)

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