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The limitation of standard topical GHK-Cu is skin penetration depth: without penetration-enhancing excipients or palmitoylation (as in Pal-GHK), absorption to the deeper dermal layers where collagen-producing fibroblasts reside is limited

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Comparing the results of previous studies revealed that in none of the conduits [14, 36, 58], presence of CNT could not increase the nerve conduction as much as autograft which is consistent with our findings

Although these symptoms improved with continued treatment, they initially worsened, indicating that neurological side effects can occur during the course of treatment