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Description

Synthesized materials were characterized by X-ray Diffraction (XRD), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), Particle Size Analyzer (PSA) Iodometric titrations and X-ray photoelectron spectroscopy (XPS)

Upon activation, NLRP3 oligomerizes and recruits ASC via PYD-PYD binding, forming a scaffold that transports procaspase-1 molecules into proximity through the CARD-CARD interaction