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doi: 10.3389/fneur.2018.00039

A., Goodman, J

Liver fibrosis is linked to oxidative stress, inflammation, and excessive deposition of extracellular matrix (ECM), and can eventually develop into cirrhosis

The chimeric version of HRS was able to rescue the loss of expression of the other component of the ESCRT-0 complex, STAM1/STAM2 and rescued the morphology of the EEA1 and SNX1-positive endosomes, consistent with its integration into a functional complex (Supplementary Fig