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For instance, induction of iNOS in microglia leads to a decrease in cellular GSH level, whereas, under comparable conditions, the GSH status of astrocytes remains largely unaffected ( - exposure ( The role of GSH as NO scavenger is also highlighted by To investigate the importance of correct GSH homeostasis for the neurotrophic capacity of NO, 2 -Tyr) protein accumulation ( Figure 1 )

The MAPEG superfamily of microsomal GSTs consists of subgroups designated I-IV, between which amino acid sequences share less than 20% identity

10.1016/j.cdtm.2020.11.002 176 XieN.ZhangL.GaoW.HuangC.HuberP