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109Barkas F, Liberopoulos E, Kei A, et al

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As with the latter, at least similar efficacy was obtained within reported values of 0.71 to 2.83 J/cm 2 regarding fluence, 0.75 ns regarding pulse duration, 3 to 5.5 mm regarding spot size, and 10 Hz regarding frequency [74,216,219,220]

CAT activity also increased (1.41.5-fold), whereas GR activity declined (2.5-fold), reflecting a pattern of early enzymatic activation followed by exhaustion with disease progression (Pavlova et al., 2025)