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Comprehensive analysis of the amino acid metabolism-related gene signature for prognosis, tumor immune microenvironment, and candidate drugs in hepatocellular carcinoma

FIGURE 5 Lapatinib Inhibits Neuronal Ferroptosis by Maintaining Glutathione Peroxidase 4 Next, we probed the molecular mechanism of lapatinibs neuroprotection against neuronal ferroptosis

10.1212/01.wnl.0000187070.35365.d7 111 FerriA.CozzolinoM.CrosioC.NenciniM.CasciatiA.GrallaE

Collectively, the above referred evidence supported the notion that inducing ferroptosis greatly contributed to hepatic steatosis in NASH/NAFLD by facilitating hepatic lipogenesis and abnormal lipid accumulation in the liver