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FIGURE 1 A comprehensive literature search was undertaken across major global and regional electronic databases (PubMed, Web of Science, CNKI, Google Scholar) from their respective inceptions to April 2025, employing a combination of Medical Subject Headings (MeSH) terms, keywords, and Boolean logic combinations (e.g., Hippophae rhamnoides AND phytochemistry) for systematic retrieval of relevant studies

To fulfill all these roles and provide protection from oxidation, intracellular GSH levels should be around 2.2 mol/mL RBCs, and the GSH/GSSG ratio should be greater than 500

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I also discuss the importance of getting your skin (and not just moles) checked for pre-cancerous and cancer growths, the role of nutrition and lifestyle factors that improve skin health and appearance, and how to improve your skin by reducing local and systemic inflammation and supporting your microbiome