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The RESV injection also increased the STZ-mediated reduction of viability of DRG and the amounts of glutathione, glutathione peroxidase, vitamin A, -carotene, and vitamin E in the brain, erythrocytes, plasma, liver, and kidney

urinalysis was normal

Renal senescence often reduces EPO production, while age-related chronic inflammation characterized by elevated cytokines such as IL-6 and TNF- impairs iron utilization and inhibits erythroid progenitor proliferation, a phenomenon referred to as anemia of inflammation or anemia of aging. Nutritional deficiencies in iron, vitamin B12, and folate further exacerbate the decline in RBC production in older adults