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In the later stages of reperfusion, the CD62L+ subpopulation releases non-lethal NETs via mtDNA, whose unmethylated CpG motifs activate the TLR9/STAT3 pathway in HSCs, promoting collagen deposition and angiogenesis

286 Compared with those in the control group, the hepatic CTGF levels and severity of liver fibrosis were lower in the hepatocyte-specific p53-deficient group, whereas the extent of hepatocyte apoptosis was similar