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The resulting trimmed and de-duplicated reads were then aligned to the Rattus norvegicus Rnor6.0 reference genome, available on ENSEMBL, using STAR aligner v.2.5.2b4 25 , producing BAM files

Technical Specifications Compounds Included: GHK-Cu, BPC-157, TB-500 Total Peptide Content: 70 mg (50mg GHK-Cu, 10mg BPC-157, 10mg TB-500) Format: Lyophilized peptide blend Purity: 9899% (COA included) Appearance: Blue-tinted and white lyophilized peptide mixture Category: Research peptide reagent Intended Use Approved for: Laboratory experimentation In-vitro biochemical assays Multi-pathway mechanistic studies Preclinical, non-human research modeling Advanced peptide interaction analysis Academic or institutional research Not approved for: Human or veterinary consumption Injection, ingestion, inhalation, or topical application Cosmetic, dermatological, or therapeutic purposes Any clinical or medical application This product is not approved by FDA, Health Canada, or similar regulatory bodies for human use

Erastin and RSL3 treatment do not trigger morphological changes or biochemical processes consistent with apoptosis, such as chromatin margination or cleavage of poly ADP-ribose polymerase (PARP) [12, 13, 17]

doi: Poon HF, Castegna A, Farr SA, Thongboonkerd V, Lynn BC, Banks WA, Morley JE, Klein JB, Butterfield DA (2004) Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain