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This dual-delivery strategy effectively co-localized antiPD-1 antibodies and curcumin within tumors and demonstrated superior therapeutic efficacy in both in vitro and in vivo models ( 5 Conclusion and future perspectives Natural metabolism-regulating agents have emerged as promising adjuvant strategies in cancer immunotherapy due to their ability to reprogram metabolic pathways and restore antitumor immunity

Abate G, Vezzoli M, Sandri M, Rungratanawanich W, Memo M, Uberti D

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doi: 10.1016/j.ajpath.2011.02.035 255 Ramezani-MoghadamMWangJHoVIseliTJAlzahraniBXuAet al