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155,156 While corticosteroids have shown limited efficacy and potential adverse effects in clinical trials, NSAIDs, particularly those with selective cyclooxygenase-2 inhibition, have demonstrated some protective effects in experimental models

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Acknowledgements This work was supported by the National Nature Science Foundation of China (No

this loss of stable ECD-ECD interaction was associated with increased motions of the RAMP-proximal loops of the CTR ECD (7-angstrom motion, measured at C of E123 ECD

These are described in this Protocol as established cardiovascular risk factors . On the other hand, some risk factors appear to influence cardiovascular risk, but the research is not as robust and conclusions about the influence of these risk factors are not as certain