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Several genetic mutations in ASD have been associated with genes coding for proteins involved in synaptic functions, such as SH3 and multiple ankyrin repeat domains 3 (SHANK), contactin-associated protein-like (CNTNAP), neuroligin (NLGN), and neurexin (NRXN)

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The cause of reflux is abnormalities in esophageal contractions, as its proper function relies on a rapid contraction to move food directly to the stomach without backflow