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Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region

The study shows that female patients with melanoma had significantly better responses to BRAFMEK-targeted therapy than male patients, and in preclinical melanoma models, elevated AR expression impaired treatment efficacy, while AR inhibition improved responses

Clin Neuropharmacol 1996, 19: 341348

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