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Oncogene 20 : 58365845

A study from Rigshospitalet found a relationship between testosterone, sex hormone-binding globulin (SHBG) and vitamin D in 300 healthy men with normal testosterone production

Together, our data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia