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In some cases, further tests may be required to identify the underlying cause, such as the Schilling test (now rare) or the detection of antibodies against intrinsic factor or gastric parietal cells

Prednisolone: Although prednisone has reduced the mineralocorticoid effect, the risk of hypokalemia exists and must be taken into account in particular in the following situations: - when potassium-losing diuretic, laxative or amphotericin B have been given concomitantly or when the patient has vomiting or diarrhea

The implications for experimental design are massive

These include measuring methylmalonic acid (MMA) and homocysteine levels in the blood