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Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

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On peut se retrouver en situation de carence si la vitamine B12 nest pas correctement absorbe du fait dune maladie digestive chronique (affection pancratique, tumeurs digestives, inflammation chronique de lintestin ) ou si elle est consomme de faon excessive par les bactries du tube digestif, en cas de dsquilibre de la flore intestinale (= dysbiose)