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J Oncol Pharm Pract

PARK2 mice had significantly higher normalized concentrations of Cyt-c (4.69 0.48 SEM, p = 0.03), 4-HNE (23.64 2.84 SEM, p = 0.03), Ox-LDL (8.02 0.82 SEM, p = 0.02), AGEs (9.84 1.13 SEM, p = 0.007) and TNF- (83.89 7.7 SEM, p = 0.002) compared to Wt mice (Cyt-c 2.88 0.38 SEM, 4-HNE 12.79 1.46 SEM, Ox-LDL 4.14 0.63 SEM, AGEs 3.37 0.67 SEM, TNF- 25.14 4.0 SEM) (Fig

Figure 3 MOS restores gut microbiota diversity, promotes Anaerococcus abundance, and modulates related metabolic pathways Gut microbiota diversity was markedly reduced in the Model group, whereas high-dose MOS treatment significantly increased the Shannon index ( Figure 4A ), partially restored the Simpson index ( Figure 4B ), and significantly elevated the Chao index ( Figure 4C )