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Mitochondrial damage and activation of the STING pathway lead to renal inflammation and fibrosis

The more meaningful caveat is that they are unapproved compounded products, so formulation and quality vary by pharmacy which makes your choice of compounder a clinical decision, not a purchasing one

May Inhibit New Fat Storage (Lipogenesis): Beyond breaking down existing fat, some preclinical studies indicate that AOD-9604 may help suppress lipogenesis-the process of creating and storing new fat cells [3]

The above-mentioned approach of functional MRS may also be helpful as it may reflect better the immediacy of fatigue and PEM, characteristic for ME/CFS