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Access this article Similar content being viewed by others Data availability Sequence files for all the treatment samples used in this study have been deposited at NCBI SRA with accession: PRJNA1082102

coli ) at both ends

This review critically highlights the complex alterations in circadian mechanisms associated with aging, including diminished transcriptional rhythmicity, epigenetic drift, mitochondrial desynchronization, and disruptions in neurotransmitter systems

2 Materials and methods 2.1 Patients and data collection Data were prospectively collected from 65 pediatric HCT recipients who underwent bone marrow transplantation after receiving busulfan IV during preparative chemotherapy at the Childrens Hospital of Fudan University