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Innerhalb der Lebewesen ist es allgegenwrtig und findet sich auch in Pflanzen, Pilzen und tierischen Zellen in natrlichem Zustand

Endocr Relat Cancer 27:245259

Increasing evidence suggests that aberrant microRNA (miRNA) expression is associated with the pathogenesis of endometriosis

For example, when cultured in selenium-deficient conditions, Jurkat cells (a human T cell model) exhibit increased spontaneous cell death [18], due to decreased expression of selenium-dependent antioxidant enzymes (i.e., selenoproteins) such as glutathione peroxidases (GPx) and thioredoxin reductases leading to excessive oxidative stress and eventually cell death