251 Pharmacological DNMT inhibitors such as azacitidine and decitabine have shown the ability to induce differentiation and reduce stemness in CSC populations, especially in hematological malignancies
However, when it undergoes the process of acetylation, which involves adding an acetyl group to a molecule, it has a greatly improved ability to cross the blood-brain barrier
Ozone treatments at LifeWorks include Hyperthermic Ozone Carbonic Acid Transdermal Technology (HOCATT), Major Autohemotherapy (MAH), and UVBI
doi: 10.3389/fendo.2026.1734644 Received 29 October 2025 Revised 30 December 2025 Accepted 08 January 2026 Published 03 February 2026 Volume 17 - 2026 Edited by Zhaoxiang Liu, Beijing Tsinghua Changgung Hospital, China Reviewed by Armel Herv Nwabo Kamdje, University of Garoua, Cameroon Anna-Mariia Shulhai, University of Parma, Italy Updates Copyright 2026 Wang, Wang, Fan, Sun, Feng, He, Li, Shang and Liu