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Cell viability and death analysis U-2 OS cells were plated in duplicate or triplicate at a density of 2,000 cells per well in a black 96-well plates (Corning, 3904) 48 h before imaging

20 reported that dextran sodium sulfate-induced colitis was attenuated in Gpx1 and catalase double knockout (KO) mice through enhancing regulatory T-cell function

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An initial inquiry into a commercial high-throughput drug screen of 4000 FDA approved molecules on cells or using animal models was quoted to take 915 months, cost over $150,000, and would require the development and validation of disease models