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A summary of their properties is presented in Table 26.1 (located at the end of the chapter)

Amin, A., Joshi, M

For these patients with advanced HCC, systemic chemotherapy remains the only choice of palliative treatment

Approximately 17% of these patients were children and adolescents, and the median age at diagnosis was 34 years.[4] In addition, in the Children's Oncology Group (COG) ARST0332 (NCT00346164) and European paediatric Soft Tissue Sarcoma Study Group (EpSSG) 2005 protocols, synovial sarcoma was the single most common histological subtype.[5] Clinical presentation The most common primary tumor location is the extremities, followed by trunk and head and neck.[4] Rarely, a synovial sarcoma may arise in the heart or pericardium or appear with a pleuropulmonary presentation.[6-9] The most common site of metastasis is the lung.[10,11] The risk of metastases is highly influenced by tumor size